Hyperosmolar Hyperglycemic State (HHS)
What is HHS?
HHS is a life-threatening complication of diabetes characterized by extremely high blood sugar (often >600 mg/dL) and severe dehydration, but WITHOUT ketones (unlike DKA).
Who gets it?
Primarily older adults with Type 2 Diabetes. It develops slowly over days to weeks.
Triggers:
- Infection (pneumonia, UTI).
- Illness or stress.
- Not drinking enough fluids.
- Certain medications (steroids, diuretics).
Symptoms:
- Extreme thirst and dry mouth.
- Frequent urination (eventually stops when severely dehydrated).
- Weakness, confusion, or altered mental state.
- Seizures or coma.
- NO fruity breath (no ketones).
Why is itdangerous?
The blood becomes "syrup-like" from extreme sugar concentration. This can cause blood clots (stroke, heart attack) and organ failure. Mortality rate is 10-20%.
Treatment:
Requires ICU admission.
- Massive IV Fluids: The priority is rehydration.
- IV Insulin: To gradually lower blood sugar (must be done slowly to avoid brain swelling).
- Electrolytes: Replacing potassium and sodium.
Prevention:
- Monitor blood sugar during illness.
- Stay hydrated (especially in hot weather or when sick).
- Seek medical attention if blood sugar is consistently >300 mg/dL.
Resources:
- American Diabetes Association: www.diabetes.org