Gigantism & Acromegaly

What is the difference?

Both are caused by a pituitary tumor producing too much Growth Hormone (GH).

  • Gigantism: Occurs in Children before bone plates close. The child grows incredibly tall (sometimes over 7 or 8 feet) and rapidly.
  • Acromegaly: Occurs in Adults after bone plates close. You don't get taller; instead, bones thicken (hands, feet, jaw) and soft tissues swell.

Why is Gigantism rare?

Pediatricians usually catch rapid growth early.

Treatment:

Both require aggressive treatment to stop the excess growth and protect the heart.

  • Surgery: To remove the pituitary tumor.
  • Medication/Radiation: To lower GH levels if surgery isn't fully effective.

Resources: